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What is health, and how do lifestyle and non-communicable diseases such as cancer affect the body?

The definition of health, the difference between communicable and non-communicable disease, risk factors for non-communicable diseases, the effect of lifestyle, the development of cancer, and the interaction of different diseases.

A focused answer to AQA GCSE Biology 4.2.2, covering the definition of health, communicable and non-communicable disease, risk factors and lifestyle, the development of cancer, and how diseases interact.

Generated by Claude Opus 4.89 min answer

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  1. What this dot point is asking
  2. What is health?
  3. Communicable and non-communicable disease
  4. The development of cancer
  5. How diseases interact
  6. Try this

What this dot point is asking

AQA wants you to define health, distinguish communicable from non-communicable disease, describe risk factors and the effect of lifestyle, explain how cancer develops, and explain how different types of disease can interact.

What is health?

Diseases are a major cause of ill health, but diet, stress and a person's life situation also affect both physical and mental health, and these factors can influence one another.

Communicable and non-communicable disease

  • Communicable diseases are caused by pathogens (bacteria, viruses, fungi, protists) and can be passed from one person to another, for example measles or flu.
  • Non-communicable diseases cannot be transmitted from person to person; they tend to last a long time and often get worse slowly. Examples include cardiovascular disease, type 2 diabetes and most cancers.

The cost of non-communicable diseases is huge, both to individuals (poorer quality of life, early death) and to society and the economy (treatment costs, lost working days).

The development of cancer

  • Benign tumours grow in one place, usually within a membrane, and do not spread to other parts of the body, so they are usually less dangerous.
  • Malignant tumours are cancers: their cells invade neighbouring tissues, and cells can break off and spread in the blood to other parts of the body, forming secondary tumours.

Both lifestyle risk factors (such as smoking and UV exposure) and genetic risk factors can contribute to cancer.

How diseases interact

Different types of disease can affect one another. For example, defects in the immune system mean a person suffers more from communicable diseases; some viruses living in cells can trigger cancers; immune reactions caused by a pathogen can trigger allergies such as skin rashes and asthma; and severe physical ill health can lead to depression and other mental illness.

Try this

Q1. Give one example of a non-communicable disease and one risk factor for it. [2 marks]

  • Cue. For example, cardiovascular disease, with smoking or a poor diet as a risk factor.

Q2. State the difference between a benign and a malignant tumour. [2 marks]

  • Cue. Benign stays in one place; malignant spreads to other parts of the body.

Exam-style practice questions

Practice questions written in the style of AQA exam questions on this dot point, with worked answer explainers. The year tag is the paper they imitate, not the source.

AQA 20204 marksA study found that the number of cases of a lung disease increased as the number of cigarettes smoked per day increased. Explain what this shows about smoking as a risk factor, and why this data alone does not prove that smoking causes the disease.
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A 4-mark question rewards interpreting data and the correlation-versus-causation idea.

The data shows a correlation: as the number of cigarettes increases, the number of cases of the disease increases, so smoking is a risk factor for the disease. The more cigarettes smoked, the higher the risk, which is a dose-response relationship that strengthens the link.

However, a correlation alone does not prove cause, because another factor could be responsible, for example smokers may also have other lifestyle differences. To establish that smoking causes the disease, scientists also need a biological mechanism (how chemicals in smoke damage the lungs) and further studies.

Markers reward identifying the positive correlation (risk factor), the dose-response, and the point that correlation does not prove causation without a mechanism.

AQA 20214 marksDescribe the difference between a benign and a malignant tumour, and explain how malignant tumours can lead to secondary tumours in other parts of the body.
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A 4-mark question rewards the difference plus the spread mechanism.

A benign tumour grows in one place, usually contained within a membrane, and does not invade other tissues, so it is not normally dangerous unless it presses on an organ. A malignant tumour is a cancer: the cells divide uncontrollably and invade neighbouring tissues.

Cells can break off a malignant tumour and travel in the blood (or lymph) to other parts of the body, where they invade and grow to form new tumours called secondary tumours. This spread is what makes malignant tumours dangerous.

Markers reward benign staying in one place, malignant invading and spreading, and cells travelling in the blood to form secondary tumours.

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